Highlights of Spain and Italy Tour

What to expect on this itinerary
Embrace the majesty of masterpieces accentuated by the allure of Medieval and Renaissance arts as you experience this handmade best of Spain and Italy tour. Follow the trail of ageless wonders that continue to attract visitors each year. The works of Raphael and Botticelli decorate historic palaces in elaborate museum displays. The surreal designs of Gaudí shape the aesthetic of the skyline in Barcelona. Gilded frescoes turn St. Mark’s Basilica into a glowing chapel and the glamorous halls of the Spanish Royal Palace sheds light on the historical importance and wealth of the monarchy.
Customizable Itinerary
Madrid – The Capital of Spain with an Introductory Tour of the City
The Spanish capital is full of energy that winds around the layers of historic streets and grand plazas. The gorgeous architecture of the Gran Via is an opulent meeting place of culture, politics, ideas, and art in with its combination of Art Deco designs and Neo-Mudéjar styles. The Telefónica Building was erected between 1926 and 1929 as Europe’s first skyscraper and it hosts a view of the future in the Spanish Telecommunications Company with a structural height of 290 feet above street level. Your flight will land at Adolfo Suárez Madrid-Barajas Airport, where your private transfer greets you upon arrival.
After spending time relaxing in your luxurious accommodations at the heart of Madrid, your guide will meet you in the lobby to provide you an authentic and thorough introduction to the city’s monuments. The tour leads you to the center of Madrid at Puerta del Sol, named for the emblem decorating the former city gate that once stood in the plaza. You find “Kilometer Zero,” a stone slab decorating the ground from which all distances on Spain’s national roads are measured. The plaza was also the scene of a historic resistance against the imposing forces of Napoleon Buonaparte in 1808. Lively cafes and elegant shops juxtapose the historical ambiance but bring a touch of contemporary charm.
What's Included:
Madrid – Discover the Grandeur of Madrid on a Palace and Prado Tour
Barcelona – Explore the Fascinating Barrí Gotic
Barcelona – Uniqueness with a Gaudí Tour and Cooking Class
Venice – A Sensational Welcome in the City on the Lagoon
Venice – the Remarkable History of Venice at St. Mark’s Square
Florence – See the Florence and the Uffizi After-Hours
Rome – The Charming Town of Arezzo en route to Rome
Rome – Monuments of Rome and Galleries of the Vatican Museum
Rome – Depart for Home
Trip Highlights
- Visit the sensational galleries of the Prado Museum to view the sensational European Masers on display including works by El Greco
- Traverse the streets of Barcelona for interactive views of Antonin Gaudí’s surrealist architecture while you spend time at the Casa Mila
- Witness the marvelous gilded mosaics that span the rounded domes, columns, and ceiling of St. Mark’s Square in Venice
- Wander the exciting rooms of the Uffizi Gallery in Florence to find the remarkable works of Renaissance painters like Botticelli
- Enjoy the flavors of Barcelona with a private cooking class celebrating the unique, authentic dishes of Catalonia
- Relish time with the magnificent Italian masters decorating the Vatican Museum including works by Raphael
- Explore the impressive grandeur of the Spanish Royal Palace in Madrid for views of elaborate Baroque and Rococo architecture and art
Detailed Description
Spain and Italy represent the pleasures of the good life with classic art, delicious cuisine, and an appreciation for the beauty of the past. Travel from Madrid to Rome and Barcelona to Venice for an exceptional blend of art, architecture, history, and flavor that reveals the depths of heritage on the Iberian and Italian peninsulas. Explore iconic monuments, cruise the cherished canals, and wander Renaissance streets of an overlooked Tuscan treasure for an insightful, enchanting experience.
The discovery will begin in Madrid, Spain as you explore the capital city. The grand streets and vibrant ambiance become an amalgamation of Spain’s diverse regional cultures. The Spanish Royal Palace, Prado Museum, and verdant grasses decorating El Retiro Park reflect the affluence and history of the classic city. Then, you will continue to Barcelona, which encompasses the vibrant differences between the fast-pace of the capital and the Mediterranean ambiance of Catalonia. The antique neighborhood of the Barrí Gotic contains the preserved medieval architecture that contrasts with contemporary images of Picasso’s artwork. The surrealist architecture of Antoni Gaudí becomes a prominent feature of the skyline in the form of La Sagrada Familia, Park Güell, and Casa Mila.
Arrive in Venice, Italy for an enchanting ambiance of a storybook to life. The marble palaces and gilded frescoes represent the affluence of the Venetian Republic. Gondolas cruise the crisscrossing canals and wind through the 118 connected islands that create the greater city. Your time in Florence will celebrate the Renaissance with captivating architecture and master artworks lining the walls of the Uffizi Gallery. The town of Arezzo captures the essence of Medieval and Renaissance architecture accentuated by the fabulous panorama overlooking the lush countryside of Tuscany. The Eternal City continues to attract visitors from around the world with promises of preserved ancient ruins and glimpses into the maintained beauty cultivated under the papacy. From the Pantheon to Vatican City, the tomb of Raphael to the works of the master adorning the walls of the former pope’s apartment, Rome remains a spectacle by combining ancient ruins, medieval streets, Renaissance art, and Baroque palaces.
Starting Price
$4,200 per person (excluding international flights)
Your Zicasso trip is fully customizable, and this sample itinerary is a starting place for your travel plans. Actual costs are dynamic, and your selection of accommodations and activities, your season of travel, and other such variables will bring this budget guideline up or down. Throughout your planning experience with your Zicasso specialist, your itinerary is designed around your budget. You can book your trip when you are satisfied with every detail. Planning your trip with a Zicasso travel specialist is a free service.
What's Included
- Accommodations
- In-country transportation
- Some or all activities and tours
- Expert trip planning
- 24x7 support during your trip
Your final trip cost will vary based on your selected accommodations, activities, meals, and other trip elements that you opt to include.
Verified Traveler Reviews
Based on 767 reviews
Zicasso’s tour operator planned the most amazing trip to Italy for us! My requirements were culture, romance, and relaxation. She delivered on every aspect. Although we missed our tour of the Vatican due to the Pope's funeral, my husband and I actually attended his funeral!! Our hotel, though planned many months before, was next to the basilica where Pope Francis was laid to rest. Talk about being a part of history!
We stayed in a beautiful converted villa to boutique hotel in Florence; got whisked away through the Tuscan countryside in a vintage Fiat 500; took cooking classes; sipped lovely wine, accompanied by excellent lunches on our winery tours; soaked in Italy's rich culture and museum scene; and even ticked the relaxation box by spending time by the pool, in the spa, and resting on our large deck overlooking the Amalfi coastline.
Every tour guide was extremely knowledgeable and personable, and it was evident they loved their jobs. Between memories of the boat ride along the Amalfi Coast, tips from the cooking classes I have already started using at home, and the cases of wine we are eagerly awaiting delivery of, my husband and I will forever hold Italy in our hearts and la dolce vita it provided us.
Talk with our tour operator; you will be glad you did!
See more
Zicasso's tour company did a wonderful job of planning our dream honeymoon! Our travel agent took into consideration our wants and wishes, and created half- and full-day activities for us throughout the trip. We were able to visit four locations (Rome, Sorrento, Florence, and Venice) while in Italy. The trip was a perfect mix of relaxation and exploration. The tour company took away the stress of traveling and allowed us to enjoy the days without worries.
See more
We had a fantastic experience for a first-time trip to Italy. I wasn't sure how this would be, considering I learned about Zicasso while trying to plan the trip myself. Zicasso put me in touch with a travel specialist and the whole team was incredibly responsive to my many, many questions. If they were ever annoyed, it didn’t show.
I really wanted a smooth experience for my family of five, including three teens, one of whom has Celiac. Our agent was great in helping plan out the experience we wanted. As you may know, it is challenging to find rooms for five in Europe, but the travel company found apartments (usually two bedrooms with a pull-out couch) in the heart of town. You can really customize what you do, but we elected to plan our own meals and handle some of our own transport. We did have one issue where the van driver taking us to the train failed to show. I got one with Uber and the travel company quickly (I mean before we got home quickly!) refunded that amount.
Our contact in Italy was amazing and patient. I can’t give her enough credit. Any time I was unsure of something, she was there. The tours were great, especially Florence and Rome. You may be able to find the companies online, but ours seems to have the connections to get the best guides.
As for meals, we didn’t have any issues. We used an app and got a few recommendations from the travel company and local guides. Even our wine-tasting tour out in Tuscany was accommodating.
I would use our travel company and Zicasso again. I think the only downside is we tried to cram a lot in and it was hot. I probably should have asked for one to two fewer or shorter walking tours, especially on days we switched cities. Otherwise, it was excellent.
See more
Our trip was fantastic. The Zicasso tour company did a wonderful job setting up our trip navigating five Italian cities. The recommendations for hotels and dining were excellent. Their local guides and drivers for exploring the cities and sites were very knowledgeable and were key in getting the most out of our trip. I highly recommend this company to anyone interested in travel to Italy. It was an awesome trip.
See more
My wife and I have been lucky enough to travel to many places around the world, but our April 2025 journey organized by Zicasso's tour company was easily one of the best. Our agent and her team thought of every detail. All we had to do was show up and enjoy these two beautiful countries!
We went to Four cities: Lisbon, Porto, San Sebastián, and Barcelona. The itineraries were thoughtfully planned to give us great experiences without wearing us out too much. And the guides in each city were fun, knowledgeable, and engaging. The transportation was always easy and on time, and the hotels were top-notch.
See more
I am so happy we worked with our Zicasso travel agent for our 11-night visit to Venice, Florence, and Rome. We had a wonderful Italian experience. Our agent was everything you hope for in a travel specialist: knowledgeable, thoughtful, helpful, gracious, and kind.
Upon hearing our initial ideas for the trip, she quickly put together a plan on how best to allot our time. Thereafter ensued exchanges regarding hotels, sightseeing, guides, and transfers. She listened to our thoughts, desires, and questions, making many useful suggestions, including hotel choices. She always prioritized our wants and concerns. She organized the travels quickly, as we contacted her only two months prior to departure.
Once we agreed to the program, she sent us a brochure PDF laying out details for each day of the trip that included hotel confirmations, transfer details, vouchers for museums, a cooking class, a Tuscany day trip with wine, cheese, and olive oil tasting, a gondola ride, Venice lagoon boat excursion, basilica entrance tickets, and guided tours of each city, the Vatican, and Colosseum.
Upon arrival in Venice, our agent met us at the airport and escorted us to our water taxi. She kept in touch with us daily, texting a reminder of the next day’s schedule, along with numbers for guides and drivers if applicable. Everything she planned went smoothly, without a single hitch.
When you begin the process with Zicasso, it feels akin to a shot in the dark. The site provides the names of two companies and you’re left to decide who to work with. I couldn’t be more pleased with the trip our agent designed. Book with her; you will be in the best of hands.
See more





