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Rome and Sicily Itineraries & Tours

Celebrate two distinctive regions of Italy that each host an iconic culture, cuisine, and history. Rome and Sicily stand as testaments to ancient and modern marvels, and their endless enchanting qualities are waiting for your discovery. Explore the variety of Italy with your Rome and Sicily itinerary from Zicasso.

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8 Day Trip IdeaFrom $3,600

Sicily Itinerary for the Experienced Wine Connoisseur

Noto, Taormina, Salina, Catania, Marzamemi

View of the city of Taormina and Mount Etna, Sicily

7 Day Trip IdeaFrom $3,200

Sicily for Two: One Week Couple’s Retreat

Palermo, Cefalu, Taormina

14 Day Trip IdeaFrom $6,300

Wonders of Rome, Sicily & The Amalfi Coast Tour

Rome, Sorrento, Pompeii, Amalfi, Capri +7 more

Boys enjoying a delicious Italian pizza.

10 Day Trip IdeaFrom $4,500

Kid-Friendly Family Tour of Italy's Highlights

Rome, Florence, Pisa, orvieto, Lucca +6 more

12 Day Trip IdeaFrom $11,600

Italian Adventure to Rome, Amalfi Coast and Sicily

Rome, Sorrento, Capri, Amalfi, Positano +4 more

Couple at a luxury resort pool surrounded by vineyards in Selinunte, Sicily

9 Day Trip IdeaFrom $4,100

Romantic Sicily Wine Tour

Palermo, Marsala, Cefalù, Erice, Selinunte

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Zicasso specializes in custom tours, vacations, and safaris tailored to your interests and preferences. From private African safaris to culinary experiences in Europe, submit a trip request to share your ideas and travel style.
2.Meet Your Travel Specialists
To ensure a personalized experience, we'll carefully handpick and introduce you to two of our top travel specialists, each with unsurpassed destination knowledge and local insight aligned to your luxury travel dreams.
3.Design Your Perfect Journey
Compare the expertise of two specialists with itineraries crafted exclusively for you. You can refine these further and choose your preferred proposal. Our unique process ensures a more creative, personalized, and expertly crafted trip.

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More Multi-Region Tours in Italy

Milan, Florence, and Rome

Rome, Florence, and Amalfi Coast

Trulli homes of Alberobello in the southern Italian region of Puglia

Southern Italy & Sicily

Rome & Amalfi Coast

Rome, Florence, and Venice

Sunset over the Grand Canal in Venice, Italy

All Italy

4.9

Reviews of Zicasso's Rome and Sicily Itineraries & Tours

Based on 2193 verified traveler reviews.

Italy Tour Review: Syracuse, Taormina, Palermo, Cooking Class, Golf, 10-Day Trip

"Our trip was extremely well organized and all the tour guides did a wonderful job. We will definitely reach out to Zicasso in the future."

Italy Vacation Review: Sicily, Temples, Cathedrals, Cooking Class, Boat Tour, 2 Weeks

"Zicasso’s travel agency planned the trip of a lifetime for us. They were attentive, communicated with us daily, and responded to any concerns."

Italy Tour Review: Sicily, Ortigia, Taormina, Positano, Capri, Palermo, Mt. Etna, Culture, Cooking Class, Hiking, 20-Day Trip

"We were very happy with Zicasso and the travel company for arranging such a fabulous trip for us and very highly recommend their services."

Italy Travel Review: Palermo, Trapani, Erice, Mazara del Vallo, Marsala, Taormina, Zingaro Reserve, Historic Sites, Wine Tasting

"The trip planning and organization done by the travel agency were amazing."

Italy Luxury Anniversary Tour Review: Sicily, Amalfi Coast, Mt. Etna, Private Yatch Tours, Cooking Classes, Winery, 12-Day Trip

"Cameron has a deep knowledge and understanding of the country, and I would absolutely use her again for future trips to Italy."

Southern Italy Luxury Vacation Review: Hilltop Town of Taormina, Greek Ruins of Agrigento, Marsala Wine Tasting, History & Food

"This travel team is an excellent agency, with an emphasis on service."